Description

An NIH-funded postdoctoral position is available immediately to conduct structural and biophysical studies of staphylococcal cell-surface proteins involved in host adherence and biofilm formation. The primary focus is to characterize the host ligand(s) for staphylococcal lectins responsible for skin colonization. The Herr Laboratory at Cincinnati Children's Hospital uses a wide range of biophysical and structural approaches to understand the structure, higher-order assembly, and ligand interactions of proteins implicated in staphylococcal pathogenesis. We have access to a cryoEM facility at the new Center for Advanced Structural Biology across the street at the University of Cincinnati College of Medicine, and we are part of a large collaborative community of scientists with expertise in structural biology and biophysics. The ideal candidate would have hands-on experience with structural biology techniques (X-ray crystallography and/or cryoEM) and expertise in cloning and protein purification. Experience with quantitative biophysical techniques (e.g., analytical ultracentrifugation, surface plasmon resonance, isothermal titration calorimetry, or circular dichroism) is highly desired, but can be learned on the job. This would be a great opportunity for a recent PhD graduate with structural experience to learn biophysical techniques or vice versa. Please send a cover letter, CV, and 2 references by email to Andrew Herr.

MAJOR DUTIES AND RESPONSIBILITIES:

• Design, execute, and record laboratory experiments, and analyze the data.
• Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department.
• Present research at laboratory meetings, journal clubs, seminars, and meetings.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
• Maintain currency in field through continuing education, literature, and seminars.
• Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures.
• Perform other duties as assigned.

Cincinnati Children's Research and Training at a Glance:

• Among the top in NIH funding for pediatric research institutions
• Over 1.4 million square feet of research laboratory space
• 900+ scientists conducting basic, translational, and clinical research
• Over 2000 publications annually in top-tier journals
• Access to Employee Resource Groups and Mentorship programs
• Postdocs have gone on to careers in academia, biotech, pharma, teaching etc.

Learn more about the Postdoctoral Fellowship Program.

Compensation and Benefits:

• Postdoctoral Research Fellows and Associates are eligible for:
  • Group Health, Dental, and Vision Insurance Plans
  • Paid Time Off
  • Retirement Plan
  • Tuition Reimbursement
  • Relocation Benefits for Eligible Hires

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Qualifications

EDUCATION/EXPERIENCE;
Required: PhD, MD or a Doctoral degree in a related field. The ideal candidate would have hands-on experience with structural biology techniques (X-ray crystallography and/or cryoEM) and expertise in cloning and protein purification.

Preferred: Experience with quantitative biophysical techniques (e.g., analytical ultracentrifugation, surface plasmon resonance, isothermal titration calorimetry, or circular dichroism) is highly desired, but can be learned on the job. This would be a great opportunity for a recent PhD graduate with structural experience to learn biophysical techniques or vice versa.

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